Development and evaluation of artemether parenteral microemulsion

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Development and Evaluation of Artemether Parenteral Microemulsion

The objective of the present investigation was to develop a parenteral microemulsion delivering artemether, a hydrophobic antimalarial drug and to evaluate antimalarial activity of the microemulsion in comparison to the marketed oily injection of artemether (Larither(®)). The microemulsion was evaluated for various parameters such as globule size, ability to withstand centrifugation and freeze-...

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Preparation and Evaluation of Aceclofenac Topical Microemulsion

A topical preparation containing aceclofenac was developed using an o/w microemulsion system. Isopropyl myristate was chosen as the oil phase as it showed a good solubilising capacity. Pseudo-ternary phase diagrams were used to obtain the concentration ranges of the oil, surfactant (Labrasol) and co-surfactant (plurol oleique) for microemulsion formation. Five different formulations were formul...

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ژورنال

عنوان ژورنال: Indian Journal of Pharmaceutical Sciences

سال: 2010

ISSN: 0250-474X

DOI: 10.4103/0250-474x.78536